Background: Chemotherapy and radiation resistance are major causes of failure in cancer treatment. The response to treatment in cancer cells depends on several mechanisms and pathways such as Janus kinases-signal transducers and activators of transcription JAK/STAT pathway. STAT1 was the first described transcription factor in the STAT family. STAT1 is activated by stimulation of signaling proteins such as type II interferon (IFN- ?) and the activated STAT1 translocates from cytoplasm to nucleus.

Chemotherapy is one of the most important methods of treatment available today for the treatment of neoplastic diseases and gives many patients an increased quality of life and a prolonged survival time (McKnight, 2003). The object of this study was to find out more about owners? views on and experiences of chemotherapy of dogs when it comes to for example quality of life, side effects and if they would make the same decision and treats their dog again in the future. A questionnaire was in the spring of 2009 sent out to the owners of 100 dogs that had been treated with chemotherapy for neoplastic diseases at Universitetsdjursjukhuset, Sveriges Lantbruksuniversitet (SLU) in Uppsala between 2002 and 2008. The response rate was 67 %.

The purpose of this study is, on the basis of institutional theory, to contribute with moreunderstanding about resistance to management accounting change and also to survey reasonsfor the resistance and how to cope with the resistance.The study is a qualitative case study and semi-structured interviews have been used tocomplement the study?s theoretical area, consisting of scientific articles.The conclusion from the study is that resistance to management accounting change can beunderstood and explained by the institutions of each organisation and its underlying structures. Afurther conclusion is, with the structures in mind there are many reasons for resistance and alsomany ways to cope with the resistance. A model has been produced in purpose to createunderstanding and to survey the resistance to management accounting change..

Chemotherapy is one of the most important methods of treatment available today for the treatment of neoplastic diseases and gives many patients an increased quality of life and a prolonged survival time (McKnight, 2003). The object of this study was to find out more about owners? views on and experiences of chemotherapy of dogs when it comes to for example quality of life, side effects and if they would make the same decision and treats their dog again in the future. A questionnaire was in the spring of 2009 sent out to the owners of 100 dogs that had been treated with chemotherapy for neoplastic diseases at Universitetsdjursjukhuset, Sveriges Lantbruksuniversitet (SLU) in Uppsala between 2002 and 2008. The response rate was 67 %.

Success in treatment with platinum-based chemotherapy against different types of cancer tumors is limited by side-effects such as hearing loss which can have a large impact on the individual`s quality of life. It is of great importance to continue with studies that address this complex of problems.Objective: The aim of this literature review is to investigate the impact of platinum-based chemotherapy on hearing in children and adolescents treated for different types of cancer.Method: A descriptive review of literature was made based on sources from 15 different studies on the impact of platinum-based chemotherapy on hearing in the target group.Results: The survey of the studies shows that platinum-based chemotherapy causes incidence of hearing loss by differing degree in the target group. Dosage of a platinum-based substance appeared to be the most significant factor. Treatment with both cisplatin and carboplatin was more ototoxic than treatment with only one of these. Greater risk for hearing loss was to a higher degree observed in younger children.

Aim: The aim of present study was to determine the frequency of taste and smell disorders occuring in patients receiving chemotherapy for cancer. Methods: The study was of an empirical cross sectional quantitative descriptive design. During one month, consecutive cancer patients at outpatient units in two Swedish hospitals were asked to participate in the study by completing a questionnaire that had been developed previously for a similar study. All participants had undergone at least 1 cycle of intravenous chemotherapy or  a minimum of seven days of oral chemotherapy. Results: A total of 102 patients completed the questionnaire.

Cancer is one of the most feared diseases in veterinary medicine today, and the incidence is higher than ever due to the fact that our companion animals live longer then they did ten to twenty years ago. Cancer is also one of the most common causes of mortality in older companion animals. This literature review will be about two of the currently most common form of cancer treatment of companion animals in Swedish animal hospitals, chemotherapy and radiation therapy. There will also be a section of general nursing care for cancer patients. The section of chemotherapy will describe the indications for choosing chemotherapy, the way to administrate chemotherapeutic drugs, describe specific chemotherapeutic drugs, potential side effects of chemotherapy, and how to handle and store chemotherapeutic drugs safely. The section of radiation therapy will describe the current devices for delivering radiation therapy, describe the indications for choosing radiation therapy and describe potential side effects that radiation therapy may cause.

Aim: The aim of this study was to determine whether or not there is evidence for the usage of ginger as an antiemetic in patients experiencing chemotherapy related nausea, based on available scientific literature.Methods: The original articles were found by using search engines PubMed and CINAHL. The selected articles were then analyzed based on their content, quality and results. Based on the results from the content analysis the articles were placed in four different themes.Results: In the first theme two of the articles found that ginger had significant effect on chemotherapy related nausea, when used in combination with regular antiemetic treatment. Two other articles said that it does not. In the second theme four studies found that different forms of ginger lessens nausea, in contrast two other articles found that it does not have any increased effect on said nausea.

The goal with this master thesis has been to evaluate and to examine the stationary resistance bridge. The resistance bridge uses a 4-point measuring to determinate the resistance, which is used in the manufacturing of the conductor. It is then used when the resistance is to be decided for coarser aluminium conductors. A conductor has to fulfil certain demands to be able to move forward in the process. One of these demands is the resistance in ohm/km, which has demands that the measure values of the resistance bridge are as true and precise as possible.

The goal with this master thesis has been to evaluate and to examine the stationary resistance bridge. The resistance bridge uses a 4-point measuring to determinate the resistance, which is used in the manufacturing of the conductor. It is then used when the resistance is to be decided for coarser aluminium conductors. A conductor has to fulfil certain demands to be able to move forward in the process. One of these demands is the resistance in ohm/km, which has demands that the measure values of the resistance bridge are as true and precise as possible. The stationary resistance bridge had been examined through various kinds of measurements to be able to see how stable the system is and how to obtain a measure value as optimized as possible.

Introduction Malignant lymphoma is the most common haematological blood cancer diagnosis. In spring 2013 a questionnaire was handed out to patients with various haematological malignancies. The results showed that the patients requested more verbal and written information about their disease and treatment. Providing information about chemotherapy and how it affects the patient's quality of life is part of the nursing care. Communication between nurse and patient is very important to share experiences and knowledge with each other Aim The aim is to describe the information and communication patients with malignant lymphoma demand, based on their own experience, in meeting with the nurse before and during curative chemotherapy treatment at a haematology outpatient clinic.

This thesis is a discourse analysis of six rape trials, with the intention to analyze how the plaintiffs?? resistance is described. The overall aim is to investigate whether there are forms of resistance that the courts find more desirable and if there are any rules for how resistance should manifest itself. I will also investigate how the rape is itself described by the plaintiff and courts, respectively. I will analyze how this affects the understanding and attitude toward what has happened.

Featured adjuvant chemotherapy treatment in women with breast cancer can lead to pain. The aim of this study was to explore, the variety of perceptions and impact of adjuvantchemotherapy-induced pain in daily life, of some women newly diagnosed with breast cancer.Inclusion criteria were participating in an ongoing stress management projectand chemotherapy of (anthracycline/taxan) in doses of 75mg² or more. Exclusioncriteria were inability to understand and communicate in Swedish and mentalillness. After ethical approval of the sub study in September 2010, women wereconsecutively included through oral and written request. Phenomenologicalapproach was used in the eight interviews and data analysis.

Based on hermeneutic tradition, the goal of this thesis is to further my understanding of what the concept of resistance means in a psychoanalytical context today, primarily within clinical practice. My methodology has been to seek an understanding of the concept of resistance by reading excerpts from the original texts of Sigmund Freud, as well as conducting interviews with practicing psychoanalysts that focus on how they relate to the notion of resistance. The idea was to then present my understanding of these sources in relation to one another. The results suggest that an understanding of the concept of resistance in a clinical context is highlighted by a dichotomy between theory and practice..

Tolerance and resistance are two different defence mechanisms within the immune system that differ from each other in many ways: However it is not clear which of the two is the most advantageous in dairy production. Resistance is described as the ability to fight a pathogen in a host. Tolerance is, on the other hand, not aggressive to the pathogen per se, but rather protects the host and its tissues. Furthermore tolerance rather offsets the toxin from, for example, a parasite whilst resistance offsets the parasite itself. Resistance is however disease specific, which means breeding for a large number of diseases is needed in order to make resistance worth the cost for the host.